SARS-CoV-2 detection, viral load and infectivity over the course of an infection

KA Walsh, K Jordan, B Clyne, D Rohde, L Drummond… - Journal of Infection, 2020 - Elsevier
Objectives To summarise the evidence on the detection pattern and viral load of SARS-CoV-
2 over the course of an infection (including any asymptomatic or pre-symptomatic phase),
and the duration of infectivity. Methods A systematic literature search was undertaken in
PubMed, Europe PubMed Central and EMBASE from 30 December 2019 to 12 May 2020.
Results We identified 113 studies conducted in 17 countries. The evidence from upper
respiratory tract samples suggests that the viral load of SARS-CoV-2 peaks around symptom …
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